Many people suffer from degenerative joint diseases such as arthritis in all over the world. scientists have not been able to grow cartilage-like tissues that are similar to cartilages seen in human knees in the lab. But this is the first time for Indian researchers that they have been able to achieve a success in developing cartilages like human knees. The cartilage developed in the lab has remained physically stable for up to 6 weeks.  Indian Institute of Technology (IIT) Delhi has been achieved a success for preparing a 3D bioprinting of cartilage using a bioink.The bioink has high concentration of bone-marrow derived cartilage stem cells, silk proteins and a some factors. The chemical composition of the bioink supports the growth of cells and long-term survival of the cells. The silk protein has different amino acids that closely resemble the amino acids present in human tissues. Just like cells are surrounded by proteins inside our body, the cells in the engineered cartilage are also surrounded by bioink that has a similar composition. “Our next step to implant this 3D bioprinted cartilage into the knee joints of animals to check if it remains stable in the knee joint and is able to integrate with the surrounding cartilage tissue,” says Prof. Ghosh.

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